Understanding Cushing’s Disease
Cushing’s disease is characterized by distinct physical features such as a moon face, buffalo hump, central obesity, and supraclavicular fat pads. These symptoms arise from an ACTH-secreting pituitary adenoma, which is a benign tumor in the pituitary gland. This condition disrupts the normal hormone balance, leading to excessive cortisol production by the adrenal glands.
The Hormonal Imbalance
The pituitary adenoma in Cushing’s disease causes an overproduction of ACTH, which in turn stimulates the adrenal glands to release cortisol continuously. This disrupts the normal feedback mechanism that regulates hormone levels, resulting in persistent high cortisol levels that affect multiple body systems.
The Role of Surgery in Treatment
Surgery is the definitive treatment for Cushing’s disease, as it directly addresses the root cause by removing the ACTH-secreting adenoma. This procedure is performed endoscopically through the nasal passage, avoiding any skull cuts. Dr. Kalyan Bommakanti, in collaboration with ENT specialist Dr. Vyshnavi Bommakanti, utilizes advanced techniques to ensure precision and safety during the operation.
Endoscopic Transnasal Approach
The endoscopic transnasal approach is a minimally invasive technique that allows surgeons to access the pituitary gland through the nose. This method, performed using a 4K camera and Joimax HD endoscope, provides high-definition visualization of the surgical area, enhancing the accuracy of tumor removal.
Post-Surgery Recovery and Outcomes
Following the removal of the adenoma, the ACTH signal ceases, leading to a rapid decrease in cortisol levels within 24 to 48 hours. Patients typically experience a gradual resolution of symptoms such as moon face and hypertension over the subsequent weeks. Dr. Kalyan Bommakanti’s extensive experience, with over 7,500 surgeries, ensures optimal outcomes for patients undergoing this complex procedure.
Why Choose Dr. Kalyan Bommakanti?
Dr. Kalyan Bommakanti is a renowned neurosurgeon specializing in pituitary and spine surgeries. His expertise in endoscopic techniques, combined with the use of Functional Dynamic EMG for precise monitoring, makes him a leading choice for patients seeking effective treatment for Cushing’s disease in Hyderabad.
Read more: the full Pituitary Adenoma patient guide.
📱 WhatsApp Dr. Kalyan’s team on 85200 03683 for an appointment.